STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling. Controls somitogenesis by sequestering the BMP-4 activity which in turn differentiates distinct subtypes of the mesoderm along the mediolateral axis. (387 aa)    
Predicted Functional Partners:
BMP7
Bone morphogenetic protein 7.
    
 0.929
BMP4
Bone morphogenetic protein 4; Negatively regulates the structure and function of the limb apical ectodermal ridge.
    
 0.916
NOG2
Noggin; Belongs to the noggin family.
  
  
0.903
BMP6
Bone morphogenetic protein 6.
    
 0.823
CHRD
Uncharacterized protein.
      
 0.822
GDF5
TGF_BETA_2 domain-containing protein.
    
 0.813
BMP5
BMP5.
    
 0.802
BMP2
Bone morphogenetic protein 2; Negatively regulates the structure and function of the limb apical ectodermal ridge.
   
 0.800
GDF7
Growth differentiation factor 7.
    
 0.712
GDF6
Growth differentiation factor 6.
    
 0.691
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.