STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N4BP1NEDD4-binding protein 1; Inhibitor of the E3 ubiquitin-protein ligase ITCH. Belongs to the N4BP1 family. (930 aa)    
Predicted Functional Partners:
CASP8
Uncharacterized protein; Belongs to the peptidase C14A family.
   
 
 0.764
FAM189A1
Family with sequence similarity 189 member A1.
      
 0.764
NEDD8
NEDD8 ubiquitin like modifier.
    
   0.748
RNF19B
Ring finger protein 19B.
   
  
 0.704
NDFIP2
Uncharacterized protein.
   
  
 0.641
RAB11FIP1
RAB11 family interacting protein 1.
      
 0.600
NEDD4
E3 ubiquitin-protein ligase.
    
 
 0.585
RNF213
Ring finger protein 213.
   
  
 0.577
USP25
Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family.
   
  
 0.543
SEC62
Translocation protein SEC62; Required for preprotein translocation.
   
  
 0.540
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.