STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MICALL2Uncharacterized protein. (629 aa)    
Predicted Functional Partners:
ACTN1
Alpha-actinin-1; F-actin cross-linking protein is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
   
 0.923
RAB8B
RAB8B, member RAS oncogene family.
    
 0.921
RAB8A
Ras-related protein Rab-8A; May be involved in vesicular trafficking and neurotransmitter release; Belongs to the small GTPase superfamily. Rab family.
    
 0.921
ACTN4
Alpha-actinin-4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. Involved in tight junction assembly in epithelial cells. May also function as a transcriptional coactivator, stimulating transcription mediated by nuclear hormone receptors. Belongs to the alpha-actinin family.
    
 0.919
RAB12
RAB12, member RAS oncogene family.
    
 
 0.576
ALS2CL
ALS2 C-terminal like.
      
 0.525
IL4R
Fibronectin type-III domain-containing protein.
  
   0.423
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.