LOC422147 protein (Gallus gallus) - STRING interaction network

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LOC422147

G_PROTEIN_RECEP_F1_2 domain-containing protein. (371 aa)

Predicted Functional Partners:

BTK

0.510

RGS21

0.509

RGS19

0.507

RGS2

0.501

RGS18

0.499

GNA11

0.499

PIK3R2

0.499

PIK3CA

0.499

PMCH

0.499

PIK3R3

0.499

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTK	GNA11	ENSGALP00000045102	ENSGALP00000005115	Tyrosine-protein kinase BTK; Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker prote [...]	Guanine nucleotide-binding protein G11 alpha-subunit.	0.712
BTK	LOC422147	ENSGALP00000045102	ENSGALP00000006530	Tyrosine-protein kinase BTK; Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker prote [...]	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.510
BTK	PIK3CA	ENSGALP00000045102	ENSGALP00000014504	Tyrosine-protein kinase BTK; Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker prote [...]	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.558
BTK	PIK3R2	ENSGALP00000045102	ENSGALP00000005414	Tyrosine-protein kinase BTK; Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker prote [...]	Uncharacterized protein.	0.535
BTK	PMCH	ENSGALP00000045102	ENSGALP00000020790	Tyrosine-protein kinase BTK; Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker prote [...]	PMCH.	0.551
GNA11	BTK	ENSGALP00000005115	ENSGALP00000045102	Guanine nucleotide-binding protein G11 alpha-subunit.	Tyrosine-protein kinase BTK; Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker prote [...]	0.712
GNA11	LOC422147	ENSGALP00000005115	ENSGALP00000006530	Guanine nucleotide-binding protein G11 alpha-subunit.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.499
GNA11	PIK3CA	ENSGALP00000005115	ENSGALP00000014504	Guanine nucleotide-binding protein G11 alpha-subunit.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.620
GNA11	PIK3R2	ENSGALP00000005115	ENSGALP00000005414	Guanine nucleotide-binding protein G11 alpha-subunit.	Uncharacterized protein.	0.577
GNA11	PIK3R3	ENSGALP00000005115	ENSGALP00000023820	Guanine nucleotide-binding protein G11 alpha-subunit.	Uncharacterized protein.	0.509
GNA11	PMCH	ENSGALP00000005115	ENSGALP00000020790	Guanine nucleotide-binding protein G11 alpha-subunit.	PMCH.	0.509
GNA11	RGS18	ENSGALP00000005115	ENSGALP00000003996	Guanine nucleotide-binding protein G11 alpha-subunit.	RGS domain-containing protein.	0.606
GNA11	RGS19	ENSGALP00000005115	ENSGALP00000072612	Guanine nucleotide-binding protein G11 alpha-subunit.	Uncharacterized protein.	0.611
GNA11	RGS2	ENSGALP00000005115	ENSGALP00000053933	Guanine nucleotide-binding protein G11 alpha-subunit.	Regulator of G-protein signaling protein 2 long isoform.	0.734
GNA11	RGS21	ENSGALP00000005115	ENSGALP00000039358	Guanine nucleotide-binding protein G11 alpha-subunit.	Regulator of G protein signaling 21.	0.612
LOC422147	BTK	ENSGALP00000006530	ENSGALP00000045102	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Tyrosine-protein kinase BTK; Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in close cooperation with the adapter protein B-cell linker prote [...]	0.510
LOC422147	GNA11	ENSGALP00000006530	ENSGALP00000005115	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Guanine nucleotide-binding protein G11 alpha-subunit.	0.499
LOC422147	PIK3CA	ENSGALP00000006530	ENSGALP00000014504	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.499
LOC422147	PIK3R2	ENSGALP00000006530	ENSGALP00000005414	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.499
LOC422147	PIK3R3	ENSGALP00000006530	ENSGALP00000023820	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.499