STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DDX21Uncharacterized protein. (676 aa)    
Predicted Functional Partners:
DHX36
DEAH-box helicase 36.
   
 
 0.993
DDX1
ATP-dependent RNA helicase DDX1; Acts as an ATP-dependent RNA helicase, able to unwind both RNA-RNA and RNA-DNA duplexes. Possesses 5' single-stranded RNA overhang nuclease activity. Acts as a positive regulator of transcription. May be involved in 3'-end cleavage and polyadenylation of pre-mRNAs. Binds DNA and RNA. Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB (By similarity). Binds (via helicase ATP-binding domain) on both short and long poly(I:C) dsRNA (By similarity).
   
 
0.975
MYBBP1A
MYB binding protein 1a.
   
 0.942
BAZ1B
Bromodomain adjacent to zinc finger domain 1B.
   
 
 0.924
DEK
SAP domain-containing protein.
     
 0.911
DHX15
Uncharacterized protein.
   
 
 0.890
SF3B1
Splicing factor 3b subunit 1.
   
 0.889
DHX33
Uncharacterized protein.
   
 
 0.839
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.
   
 0.829
ERCC6
ERCC excision repair 6, chromatin remodeling factor.
   
 0.806
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (18%) [HD]