STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANAPC5Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). (756 aa)    
Predicted Functional Partners:
CDC27
Uncharacterized protein.
   
 0.999
ANAPC4
Anaphase promoting complex subunit 4.
   
 0.999
ANAPC2
Anaphase promoting complex subunit 2; Belongs to the cullin family.
    
 0.999
ANAPC7
Anaphase promoting complex subunit 7.
   
 0.998
CDC23
Cell division cycle 23.
   
 0.998
CDC16
TPR_REGION domain-containing protein.
   
 0.998
ANAPC1
Anaphase promoting complex subunit 1.
   
 0.998
ANAPC10
DOC domain-containing protein.
   
 0.998
ENSGALP00000071775
RING-type domain-containing protein.
    
 0.998
FZR1
WD_REPEATS_REGION domain-containing protein.
    
 0.997
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.