node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BACH1 | CUL1 | ENSGALP00000025472 | ENSGALP00000046909 | BTB domain and CNC homolog 1. | Cullin 1; Belongs to the cullin family. | 0.652 |
BACH1 | MAFG | ENSGALP00000025472 | ENSGALP00000052002 | BTB domain and CNC homolog 1. | Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. May be involved in signal transduction of extracellula [...] | 0.670 |
BACH1 | MAFK | ENSGALP00000025472 | ENSGALP00000046925 | BTB domain and CNC homolog 1. | Transcription factor MafK; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. | 0.978 |
BACH1 | RBX1 | ENSGALP00000025472 | ENSGALP00000019539 | BTB domain and CNC homolog 1. | RING-type domain-containing protein. | 0.575 |
BACH1 | SKP1 | ENSGALP00000025472 | ENSGALP00000010447 | BTB domain and CNC homolog 1. | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity). | 0.607 |
BACH2 | MAFG | ENSGALP00000072471 | ENSGALP00000052002 | BTB domain and CNC homolog 2. | Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. May be involved in signal transduction of extracellula [...] | 0.900 |
BACH2 | MAFK | ENSGALP00000072471 | ENSGALP00000046925 | BTB domain and CNC homolog 2. | Transcription factor MafK; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. | 0.871 |
CUL1 | BACH1 | ENSGALP00000046909 | ENSGALP00000025472 | Cullin 1; Belongs to the cullin family. | BTB domain and CNC homolog 1. | 0.652 |
CUL1 | MAFK | ENSGALP00000046909 | ENSGALP00000046925 | Cullin 1; Belongs to the cullin family. | Transcription factor MafK; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. | 0.649 |
CUL1 | NFE2L2 | ENSGALP00000046909 | ENSGALP00000074218 | Cullin 1; Belongs to the cullin family. | BZIP domain-containing protein. | 0.590 |
CUL1 | RBX1 | ENSGALP00000046909 | ENSGALP00000019539 | Cullin 1; Belongs to the cullin family. | RING-type domain-containing protein. | 0.999 |
CUL1 | SKP1 | ENSGALP00000046909 | ENSGALP00000010447 | Cullin 1; Belongs to the cullin family. | S-phase kinase-associated protein 1; Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1 (By similarity). | 0.999 |
DDX24 | MAFK | ENSGALP00000017671 | ENSGALP00000046925 | DEAD-box helicase 24. | Transcription factor MafK; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. | 0.610 |
ENSGALP00000070665 | MAFG | ENSGALP00000070665 | ENSGALP00000052002 | Nuclear factor, erythroid 2. | Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. May be involved in signal transduction of extracellula [...] | 0.794 |
ENSGALP00000070665 | MAFK | ENSGALP00000070665 | ENSGALP00000046925 | Nuclear factor, erythroid 2. | Transcription factor MafK; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. | 0.664 |
MAFG | BACH1 | ENSGALP00000052002 | ENSGALP00000025472 | Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. May be involved in signal transduction of extracellula [...] | BTB domain and CNC homolog 1. | 0.670 |
MAFG | BACH2 | ENSGALP00000052002 | ENSGALP00000072471 | Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. May be involved in signal transduction of extracellula [...] | BTB domain and CNC homolog 2. | 0.900 |
MAFG | ENSGALP00000070665 | ENSGALP00000052002 | ENSGALP00000070665 | Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. May be involved in signal transduction of extracellula [...] | Nuclear factor, erythroid 2. | 0.794 |
MAFG | MAFK | ENSGALP00000052002 | ENSGALP00000046925 | Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. May be involved in signal transduction of extracellula [...] | Transcription factor MafK; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. | 0.789 |
MAFG | NFE2L1 | ENSGALP00000052002 | ENSGALP00000035379 | Transcription factor MafG; Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Transcription factor, component of erythroid-specific transcription factor NF-E2. May be involved in signal transduction of extracellula [...] | Endoplasmic reticulum membrane sensor NFE2L1; [Endoplasmic reticulum membrane sensor NFE2L1]: Endoplasmic reticulum membrane sensor that translocates into the nucleus in response to various stresses to act as a transcription factor (By similarity). Constitutes a precursor of the transcription factor NRF1 (By similarity). Able to detect various cellular stresses, such as cholesterol excess, oxidative stress or proteasome inhibition (By similarity). In response to stress, it is released from the endoplasmic reticulum membrane following cleavage and translocates into the nucleus to form t [...] | 0.878 |