STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (382 aa)    
Predicted Functional Partners:
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
 
 
 0.927
PRKX
Uncharacterized protein; Belongs to the protein kinase superfamily.
 
 
 0.919
SGK2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
 
  
 
 0.865
AKAP10
A-kinase anchoring protein 10.
    
 0.769
RPS6KB1
Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
 
  
 
 0.699
AKAP1
A-kinase anchoring protein 1.
   
 0.670
GPR161
G protein-coupled receptor 161; Belongs to the G-protein coupled receptor 1 family.
    
  0.616
RPS6KB2
Ribosomal protein S6 kinase B2.
 
  
 
 0.601
FAM103A1
Uncharacterized protein.
      
 0.601
ACVR1
Activin receptor type-1; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin (By similarity).
   
 
 0.597
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.