STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RALGPS2Ras-specific guanine nucleotide-releasing factor RalGPS1; Guanine nucleotide exchange factor. May be involved in cytoskeletal organization. (584 aa)    
Predicted Functional Partners:
TTC33
Tetratricopeptide repeat domain 33.
      
 0.745
GRB2
Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.
   
 
 0.714
VPS50
Syndetin; Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
      
 0.684
RALA
RAS like proto-oncogene A.
    
 
 0.649
ABHD12B
AB hydrolase-1 domain-containing protein.
      
 0.628
GASK1B
Golgi associated kinase 1B.
      
 0.628
MAP3K5
Mitogen-activated protein kinase kinase kinase 5.
   
  
 0.601
PMS1
HMG box domain-containing protein.
      
 0.601
TOM1L2
Uncharacterized protein.
      
 0.601
EGFLAM
EGF like, fibronectin type III and laminin G domains.
      
 0.594
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.