STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRPSAP2Phosphoribosyl pyrophosphate synthase-associated protein 2; Seems to play a negative regulatory role in 5-phosphoribose 1-diphosphate synthesis. (369 aa)    
Predicted Functional Partners:
PRPSAP1
Phosphoribosyl pyrophosphate synthetase associated protein 1.
  
 
0.930
PRPS1L1
Pribosyltran_N domain-containing protein.
  
0.880
PRPS2
Ribose-phosphate pyrophosphokinase 2; Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis; Belongs to the ribose-phosphate pyrophosphokinase family.
  
0.880
ENSGALP00000073898
S-AdoMet_synt_C domain-containing protein.
   
  
 0.849
RPS15
40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.
  
 
 0.779
LOC101748254
Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.766
BDH1A
D-beta-hydroxybutyrate dehydrogenase, mitochondrial; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
      
 0.764
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.761
BCKDHB
Transket_pyr domain-containing protein.
   
 0.761
GART-B
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
  
  
 0.703
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.