STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLAUUrokinase-type plasminogen activator chain A; Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. (434 aa)    
Predicted Functional Partners:
VTN
SMB domain-containing protein.
   
 
 0.949
MMP9
Uncharacterized protein.
   
 
 0.838
TARP
Uncharacterized protein.
    
   0.828
SERPINF2
Serpin family F member 2; Belongs to the serpin family.
   
 
 0.785
LOC101748744
Serine protease; Belongs to the peptidase S1B family.
      
 0.767
SERPINE2
SERPIN domain-containing protein; Belongs to the serpin family.
   
 
 0.762
ENSGALP00000073333
Ig-like domain-containing protein.
    
   0.751
MMP2
72 kDa type IV collagenase; Belongs to the peptidase M10A family.
   
 
 0.725
COL3A1
Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.
   
 
 0.709
EGF
Uncharacterized protein.
      
 0.687
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.