STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (502 aa)    
Predicted Functional Partners:
MTOR
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.992
RPS6
40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA; Belongs to the eukaryotic ribosomal protein eS6 family.
    
 0.979
RPTOR
Regulatory associated protein of MTOR complex 1.
    
 0.978
PDPK1
Protein kinase domain-containing protein.
  
0.971
MLST8
MTOR associated protein, LST8 homolog.
 
  
 0.957
IRS1
Insulin receptor substrate 1.
    
 0.943
DEPDC6
Uncharacterized protein.
    
 0.934
EIF4B
Eukaryotic translation initiation factor 4B.
    
 0.933
DEPTOR
Uncharacterized protein.
    
 0.929
PPP2CA
Serine/threonine-protein phosphatase.
   
 0.927
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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