node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BRD9 | BRDT | ENSGALP00000070852 | ENSGALP00000009694 | Uncharacterized protein. | Bromodomain testis associated. | 0.761 |
BRD9 | BRPF3 | ENSGALP00000070852 | ENSGALP00000070100 | Uncharacterized protein. | Bromodomain and PHD finger containing 3. | 0.843 |
BRD9 | HIST1H4B | ENSGALP00000070852 | ENSGALP00000049875 | Uncharacterized protein. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.565 |
BRDT | BRD9 | ENSGALP00000009694 | ENSGALP00000070852 | Bromodomain testis associated. | Uncharacterized protein. | 0.761 |
BRDT | BRPF3 | ENSGALP00000009694 | ENSGALP00000070100 | Bromodomain testis associated. | Bromodomain and PHD finger containing 3. | 0.655 |
BRDT | DMAP1 | ENSGALP00000009694 | ENSGALP00000069574 | Bromodomain testis associated. | DNA methyltransferase 1 associated protein 1. | 0.602 |
BRDT | E2F1 | ENSGALP00000009694 | ENSGALP00000004806 | Bromodomain testis associated. | Transcription factor E2F1; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA bindi [...] | 0.615 |
BRDT | ENSGALP00000044025 | ENSGALP00000009694 | ENSGALP00000044025 | Bromodomain testis associated. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.665 |
BRDT | FBXO43 | ENSGALP00000009694 | ENSGALP00000056901 | Bromodomain testis associated. | F-box protein 43. | 0.703 |
BRDT | HIST1H4B | ENSGALP00000009694 | ENSGALP00000049875 | Bromodomain testis associated. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.664 |
BRDT | JMJD6 | ENSGALP00000009694 | ENSGALP00000002781 | Bromodomain testis associated. | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Dioxygenase that can both act as a arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5- hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Regulates RNA splicing by mediating 5- hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. Hydroxylates its own N-terminus, which is required for homooligomerization. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by it [...] | 0.742 |
BRDT | NSD3 | ENSGALP00000009694 | ENSGALP00000073400 | Bromodomain testis associated. | Nuclear receptor binding SET domain protein 3. | 0.603 |
BRDT | TAF7 | ENSGALP00000009694 | ENSGALP00000045227 | Bromodomain testis associated. | TAFII55_N domain-containing protein. | 0.687 |
BRPF3 | BRD9 | ENSGALP00000070100 | ENSGALP00000070852 | Bromodomain and PHD finger containing 3. | Uncharacterized protein. | 0.843 |
BRPF3 | BRDT | ENSGALP00000070100 | ENSGALP00000009694 | Bromodomain and PHD finger containing 3. | Bromodomain testis associated. | 0.655 |
BRPF3 | HIST1H4B | ENSGALP00000070100 | ENSGALP00000049875 | Bromodomain and PHD finger containing 3. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.623 |
DMAP1 | BRDT | ENSGALP00000069574 | ENSGALP00000009694 | DNA methyltransferase 1 associated protein 1. | Bromodomain testis associated. | 0.602 |
DMAP1 | HIST1H4B | ENSGALP00000069574 | ENSGALP00000049875 | DNA methyltransferase 1 associated protein 1. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.511 |
E2F1 | BRDT | ENSGALP00000004806 | ENSGALP00000009694 | Transcription factor E2F1; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis. Blocks adipocyte differentiation by binding to specific promoters repressing CEBPA bindi [...] | Bromodomain testis associated. | 0.615 |
ENSGALP00000044025 | BRDT | ENSGALP00000044025 | ENSGALP00000009694 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Bromodomain testis associated. | 0.665 |