PAK2 protein (Gallus gallus) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

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[Homology]

Score

PAK2

Non-specific serine/threonine protein kinase. (521 aa)

Predicted Functional Partners:

CDC42

0.980

RAC1

0.967

ARHGEF6

0.965

NCK1

0.961

ARHGEF7

0.960

RAC2

0.937

RAC3

0.937

LOC420419

0.927

MAP3K2

0.925

MAP3K3

0.922

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF6	ARHGEF7	ENSGALP00000010376	ENSGALP00000067519	Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF).	Rho guanine nucleotide exchange factor 7.	0.900
ARHGEF6	CDC42	ENSGALP00000010376	ENSGALP00000065867	Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF).	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	0.756
ARHGEF6	NCK1	ENSGALP00000010376	ENSGALP00000066848	Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF).	Cytoplasmic protein.	0.637
ARHGEF6	PAK2	ENSGALP00000010376	ENSGALP00000010358	Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF).	Non-specific serine/threonine protein kinase.	0.965
ARHGEF6	RAC1	ENSGALP00000010376	ENSGALP00000011538	Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF).	GTPase cRac1A.	0.949
ARHGEF6	RAC2	ENSGALP00000010376	ENSGALP00000037001	Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF).	Uncharacterized protein.	0.923
ARHGEF6	RAC3	ENSGALP00000010376	ENSGALP00000045177	Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF).	GTPase cRac1B.	0.920
ARHGEF7	ARHGEF6	ENSGALP00000067519	ENSGALP00000010376	Rho guanine nucleotide exchange factor 7.	Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF).	0.900
ARHGEF7	CDC42	ENSGALP00000067519	ENSGALP00000065867	Rho guanine nucleotide exchange factor 7.	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	0.899
ARHGEF7	NCK1	ENSGALP00000067519	ENSGALP00000066848	Rho guanine nucleotide exchange factor 7.	Cytoplasmic protein.	0.628
ARHGEF7	PAK2	ENSGALP00000067519	ENSGALP00000010358	Rho guanine nucleotide exchange factor 7.	Non-specific serine/threonine protein kinase.	0.960
ARHGEF7	RAC1	ENSGALP00000067519	ENSGALP00000011538	Rho guanine nucleotide exchange factor 7.	GTPase cRac1A.	0.920
ARHGEF7	RAC2	ENSGALP00000067519	ENSGALP00000037001	Rho guanine nucleotide exchange factor 7.	Uncharacterized protein.	0.920
ARHGEF7	RAC3	ENSGALP00000067519	ENSGALP00000045177	Rho guanine nucleotide exchange factor 7.	GTPase cRac1B.	0.920
CDC42	ARHGEF6	ENSGALP00000065867	ENSGALP00000010376	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF).	0.756
CDC42	ARHGEF7	ENSGALP00000065867	ENSGALP00000067519	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	Rho guanine nucleotide exchange factor 7.	0.899
CDC42	NCK1	ENSGALP00000065867	ENSGALP00000066848	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	Cytoplasmic protein.	0.884
CDC42	PAK2	ENSGALP00000065867	ENSGALP00000010358	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	Non-specific serine/threonine protein kinase.	0.980
CDC42	RAC1	ENSGALP00000065867	ENSGALP00000011538	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	GTPase cRac1A.	0.798
CDC42	RAC2	ENSGALP00000065867	ENSGALP00000037001	Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...]	Uncharacterized protein.	0.640