STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF6Rho guanine nucleotide exchange factor 6; Acts as a RAC1 guanine nucleotide exchange factor (GEF). (773 aa)    
Predicted Functional Partners:
PAK3
Non-specific serine/threonine protein kinase.
    
 0.975
PAK2
Non-specific serine/threonine protein kinase.
   
 0.965
GIT1
ANK_REP_REGION domain-containing protein.
   
 0.960
PAK5
Non-specific serine/threonine protein kinase.
    
 0.955
PAK1
Non-specific serine/threonine protein kinase.
    
 0.953
RAC1
GTPase cRac1A.
   
 0.949
PAK4
Non-specific serine/threonine protein kinase.
    
 0.935
PAK6
Protein kinase domain-containing protein.
    
 0.935
RAC2
Uncharacterized protein.
   
 0.923
ARHGEF12
Rho guanine nucleotide exchange factor 12.
   
 0.921
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.