ZFYVE27 protein (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ZFYVE27

Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections. (413 aa)

Predicted Functional Partners:

VAPA

0.883

FYCO1

0.834

REEP1

0.808

GPBP1L1

0.785

PDZD8

0.751

RANBP10

0.711

VAPB

0.697

ATL1

0.681

APBB1

0.681

ATL2

0.671

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBB1	ZFYVE27	ENSGALP00000071078	ENSGALP00000042307	Amyloid beta precursor protein binding family B member 1.	Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections.	0.681
ATL1	REEP1	ENSGALP00000060356	ENSGALP00000025409	Atlastin GTPase 1.	Receptor expression-enhancing protein.	0.819
ATL1	ZFYVE27	ENSGALP00000060356	ENSGALP00000042307	Atlastin GTPase 1.	Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections.	0.681
ATL2	REEP1	ENSGALP00000044940	ENSGALP00000025409	Atlastin GTPase 2.	Receptor expression-enhancing protein.	0.808
ATL2	ZFYVE27	ENSGALP00000044940	ENSGALP00000042307	Atlastin GTPase 2.	Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections.	0.671
FYCO1	VAPA	ENSGALP00000044662	ENSGALP00000055161	Uncharacterized protein.	MSP domain-containing protein.	0.585
FYCO1	ZFYVE27	ENSGALP00000044662	ENSGALP00000042307	Uncharacterized protein.	Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections.	0.834
GPBP1L1	RANBP10	ENSGALP00000016692	ENSGALP00000002189	Uncharacterized protein.	RAN binding protein 10.	0.974
GPBP1L1	ZFYVE27	ENSGALP00000016692	ENSGALP00000042307	Uncharacterized protein.	Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections.	0.785
PDZD8	VAPA	ENSGALP00000042332	ENSGALP00000055161	PDZ domain containing 8.	MSP domain-containing protein.	0.424
PDZD8	VAPB	ENSGALP00000042332	ENSGALP00000012193	PDZ domain containing 8.	MSP domain-containing protein.	0.594
PDZD8	ZFYVE27	ENSGALP00000042332	ENSGALP00000042307	PDZ domain containing 8.	Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections.	0.751
RANBP10	GPBP1L1	ENSGALP00000002189	ENSGALP00000016692	RAN binding protein 10.	Uncharacterized protein.	0.974
RANBP10	ZFYVE27	ENSGALP00000002189	ENSGALP00000042307	RAN binding protein 10.	Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections.	0.711
REEP1	ATL1	ENSGALP00000025409	ENSGALP00000060356	Receptor expression-enhancing protein.	Atlastin GTPase 1.	0.819
REEP1	ATL2	ENSGALP00000025409	ENSGALP00000044940	Receptor expression-enhancing protein.	Atlastin GTPase 2.	0.808
REEP1	VAPB	ENSGALP00000025409	ENSGALP00000012193	Receptor expression-enhancing protein.	MSP domain-containing protein.	0.427
REEP1	ZFYVE27	ENSGALP00000025409	ENSGALP00000042307	Receptor expression-enhancing protein.	Protrudin; Key regulator of RAB11-dependent vesicular trafficking during neurite extension through polarized membrane transport. Promotes axonal elongation and contributes to the establishment of neuronal cell polarity. Involved in nerve growth factor-induced neurite formation in VAPA-dependent manner. Contributes to both the formation and stabilization of the tubular ER network. Involved in ER morphogenesis by regulating the sheet-to-tubule balance and possibly the density of tubule interconnections.	0.808
VAPA	FYCO1	ENSGALP00000055161	ENSGALP00000044662	MSP domain-containing protein.	Uncharacterized protein.	0.585
VAPA	PDZD8	ENSGALP00000055161	ENSGALP00000042332	MSP domain-containing protein.	PDZ domain containing 8.	0.424

page 1 of 2

Server load: low (20%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Textmining

Neighborhood

Databases

Fusion

© STRING Consortium 2023

Credits

Access

Info

About