STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTFDC1Replication termination factor 2; Replication termination factor which is a component of the elongating replisome. Interacts with nascent DNA. Belongs to the rtf2 family. (306 aa)    
Predicted Functional Partners:
RTF1
RTF1 homolog, Paf1/RNA polymerase II complex component.
   
  
 0.880
EXD2
3'-5' exonuclease domain-containing protein.
      
 0.677
ZFAND4
Zinc finger AN1-type containing 4.
      
 0.630
CCDC130
Coiled-coil domain containing 130.
      
 0.625
SMU1
WD40 repeat-containing protein SMU1; Involved in pre-mRNA splicing as a component of the spliceosome (By similarity). Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity). Required for normal accumulation of IK (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity). Belongs to the WD repeat SMU1 family.
   
  
 0.544
SPACA9
Uncharacterized protein.
      
 0.526
SPATA16
Spermatogenesis associated 16.
      
 0.520
FAM71D
DUF3699 domain-containing protein.
      
 0.518
KCTD19
Potassium channel tetramerization domain containing 19.
      
 0.513
ESS2
Ess-2 splicing factor homolog.
      
 0.512
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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