STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CELF1CUGBP Elav-like family member 1; RNA-binding protein that may be involved in pre-mRNA alternative splicing, mRNA translation activation and stability. Belongs to the CELF/BRUNOL family. (512 aa)    
Predicted Functional Partners:
MBNL1
Muscleblind-like protein 1; Involved in pre-mRNA alternative splicing regulation. Binds to CUG triplet repeat in RNA (By similarity); Belongs to the muscleblind family.
   
 
 0.924
MBNL2
Muscleblind-like 2 isoform 1.
   
 
 0.867
MBNL3
Uncharacterized protein.
   
 
 0.866
CLCN1
Chloride channel protein.
      
 0.749
SRSF1
Serine/arginine-rich splicing factor 1; May play a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing.
   
  
 0.737
CELF4-2
Uncharacterized protein.
 
    
 0.706
TMEM184B
Uncharacterized protein.
   
  
 0.706
CNBP
Cellular nucleic acid-binding protein; Single-stranded DNA-binding protein, with specificity to the sterol regulatory element (SRE). Involved in sterol-mediated repression; To S.pombe BYR3 and to retroviral nucleic acid binding proteins (NBP).
      
 0.680
RBM24
RNA-binding protein 24; Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embry [...]
   
  
 0.662
IGF2BP3
Insulin-like growth factor 2 mRNA-binding protein 3; RNA-binding factor that may recruit target transcripts to cytoplasmic protein-RNA complexes (mRNPs). This transcript 'caging' into mRNPs allows mRNA transport and transient storage. It also modulates the rate and location at which target transcripts encounter the translational apparatus and shields them from endonuclease attacks or microRNA-mediated degradation (By similarity); Belongs to the RRM IMP/VICKZ family.
    
 
 0.645
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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