STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PACSIN3Uncharacterized protein. (458 aa)    
Predicted Functional Partners:
PACSIN2
Protein kinase C and casein kinase substrate in neurons protein 2; Regulates the morphogenesis and endocytosis of caveolae (By similarity). Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus.
  
0.883
PACSIN1
Protein kinase C and casein kinase substrate in neurons 1.
  
 
0.857
CNIH1
Uncharacterized protein.
      
 0.683
CARD19
CARD domain-containing protein.
      
 0.673
CNIH4
Cornichon family AMPA receptor auxiliary protein 4.
   
  
 0.640
CCDC85A
Coiled-coil domain containing 85A.
      
 0.600
BUD13
BUD13 homolog.
   
  
 0.590
CNIH3
Protein cornichon homolog 2; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs) (By similarity). Plays an important role in the proper development of cranial nerves by facilitating the secretion of HBEGF; Belongs to the cornichon family.
      
 0.583
KPNA7
Importin subunit alpha; Belongs to the importin alpha family.
      
 0.537
NUP43
Nucleoporin 43.
      
 0.534
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.