node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAAT5L | SLC15A1 | ENSGALP00000001020 | ENSGALP00000027228 | Amino acid transporter. | Peptide transporter PEPT1. | 0.855 |
EAAT5L | SLC2A2 | ENSGALP00000001020 | ENSGALP00000015129 | Amino acid transporter. | Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. Also able to mediate the transport of dehydroascorbate. | 0.778 |
G6PC | G6PC2 | ENSGALP00000057482 | ENSGALP00000017702 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.903 |
G6PC | GCK | ENSGALP00000057482 | ENSGALP00000053403 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Phosphotransferase. | 0.985 |
G6PC | INS | ENSGALP00000057482 | ENSGALP00000010567 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.721 |
G6PC | SLC2A2 | ENSGALP00000057482 | ENSGALP00000015129 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. Also able to mediate the transport of dehydroascorbate. | 0.777 |
G6PC2 | G6PC | ENSGALP00000017702 | ENSGALP00000057482 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.903 |
G6PC2 | GCK | ENSGALP00000017702 | ENSGALP00000053403 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Phosphotransferase. | 0.985 |
G6PC2 | INS | ENSGALP00000017702 | ENSGALP00000010567 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.718 |
G6PC2 | SLC2A2 | ENSGALP00000017702 | ENSGALP00000015129 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. Also able to mediate the transport of dehydroascorbate. | 0.813 |
GCG | GCK | ENSGALP00000032494 | ENSGALP00000053403 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. | Phosphotransferase. | 0.440 |
GCG | INS | ENSGALP00000032494 | ENSGALP00000010567 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.965 |
GCG | SLC2A2 | ENSGALP00000032494 | ENSGALP00000015129 | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. | Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. Also able to mediate the transport of dehydroascorbate. | 0.775 |
GCK | G6PC | ENSGALP00000053403 | ENSGALP00000057482 | Phosphotransferase. | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.985 |
GCK | G6PC2 | ENSGALP00000053403 | ENSGALP00000017702 | Phosphotransferase. | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.985 |
GCK | GCG | ENSGALP00000053403 | ENSGALP00000032494 | Phosphotransferase. | Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. | 0.440 |
GCK | INS | ENSGALP00000053403 | ENSGALP00000010567 | Phosphotransferase. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.843 |
GCK | SLC2A2 | ENSGALP00000053403 | ENSGALP00000015129 | Phosphotransferase. | Solute carrier family 2, facilitated glucose transporter member 2; Facilitative hexose transporter that mediates the transport of glucose and fructose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. Also able to mediate the transport of dehydroascorbate. | 0.866 |
INS | G6PC | ENSGALP00000010567 | ENSGALP00000057482 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.721 |
INS | G6PC2 | ENSGALP00000010567 | ENSGALP00000017702 | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.718 |