node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EGF | HGF | ENSGALP00000044972 | ENSGALP00000049829 | Uncharacterized protein. | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.985 |
EGF | PDGFA | ENSGALP00000044972 | ENSGALP00000062006 | Uncharacterized protein. | Platelet-derived growth factor A chain long form; Belongs to the PDGF/VEGF growth factor family. | 0.931 |
EGF | PDGFB | ENSGALP00000044972 | ENSGALP00000019858 | Uncharacterized protein. | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. | 0.949 |
EGF | PDGFC | ENSGALP00000044972 | ENSGALP00000015259 | Uncharacterized protein. | Platelet-derived growth factor C, receptor-binding form; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, in angiogenesis and blood vessel development (By similarity). | 0.907 |
EGF | PDGFD | ENSGALP00000044972 | ENSGALP00000067220 | Uncharacterized protein. | Uncharacterized protein; Belongs to the PDGF/VEGF growth factor family. | 0.916 |
EGF | PDGFRA | ENSGALP00000044972 | ENSGALP00000064586 | Uncharacterized protein. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound he [...] | 0.974 |
EGF | PDGFRB | ENSGALP00000044972 | ENSGALP00000043875 | Uncharacterized protein. | Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.957 |
EGF | PGF | ENSGALP00000044972 | ENSGALP00000065908 | Uncharacterized protein. | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. | 0.949 |
EGF | VEGFC | ENSGALP00000044972 | ENSGALP00000017608 | Uncharacterized protein. | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.957 |
EGF | VEGFD | ENSGALP00000044972 | ENSGALP00000055963 | Uncharacterized protein. | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. | 0.934 |
HGF | EGF | ENSGALP00000049829 | ENSGALP00000044972 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Uncharacterized protein. | 0.985 |
HGF | PDGFA | ENSGALP00000049829 | ENSGALP00000062006 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Platelet-derived growth factor A chain long form; Belongs to the PDGF/VEGF growth factor family. | 0.918 |
HGF | PDGFB | ENSGALP00000049829 | ENSGALP00000019858 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. | 0.934 |
HGF | PDGFC | ENSGALP00000049829 | ENSGALP00000015259 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Platelet-derived growth factor C, receptor-binding form; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, in angiogenesis and blood vessel development (By similarity). | 0.907 |
HGF | PDGFD | ENSGALP00000049829 | ENSGALP00000067220 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Uncharacterized protein; Belongs to the PDGF/VEGF growth factor family. | 0.905 |
HGF | PDGFRA | ENSGALP00000049829 | ENSGALP00000064586 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound he [...] | 0.783 |
HGF | PDGFRB | ENSGALP00000049829 | ENSGALP00000043875 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Platelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.767 |
HGF | PGF | ENSGALP00000049829 | ENSGALP00000065908 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Placental growth factor; Belongs to the PDGF/VEGF growth factor family. | 0.954 |
HGF | VEGFC | ENSGALP00000049829 | ENSGALP00000017608 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. | 0.955 |
HGF | VEGFD | ENSGALP00000049829 | ENSGALP00000055963 | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. | 0.938 |