STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDCD10Programmed cell death protein 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development. Belongs to the PDCD10 family. (212 aa)    
Predicted Functional Partners:
STK26
Protein kinase domain-containing protein.
   
 
 0.997
CCM2
PID domain-containing protein.
    
 
 0.985
MOB4
MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family.
   
 
 0.954
CTTNBP2NL
CTTNBP2 N-terminal like.
    
 
 0.945
SLMAP
FHA domain-containing protein.
   
 
 0.942
STK24
Protein kinase domain-containing protein.
   
 
 0.928
TRAF3IP3
TRAF3 interacting protein 3.
    
 
 0.926
CCM2L
CCM2 like scaffold protein.
    
 
 0.915
KRIT1
Uncharacterized protein.
   
 
 0.911
STK25
Protein kinase domain-containing protein.
    
 
 0.901
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.