STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CLCN3Chloride channel protein. (866 aa)    
Predicted Functional Partners:
EXOSC10
HRDC domain-containing protein.
     
 0.640
FBF1
Fas-binding factor 1 homolog; Keratin-binding protein required for epithelial cell polarization. Required for ciliogenesis (By similarity).
      
 0.625
CCDC171
Coiled-coil domain containing 171.
    
 
 0.599
PPP1R14C
Protein phosphatase 1 regulatory inhibitor subunit 14C.
      
 0.586
FARSB
B5 domain-containing protein.
      
 0.538
ITSN2
Intersectin 2.
   
  
 0.528
NMNAT3
Nicotinamide-nucleotide adenylyltransferase.
      
 0.526
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
   
  
 0.524
TSNARE1
t-SNARE domain containing 1.
      
 0.524
MCOLN1
Mucolipin 1.
    
 
 0.517
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.