Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MDM1Nuclear protein MDM1; Microtubule-binding protein that negatively regulates centriole duplication. Binds to and stabilizes microtubules. Belongs to the MDM1 family. (738 aa)    
Predicted Functional Partners:
DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2; Serine/threonine-protein kinase involved in the control of mitotic transition and the regulation of cellular growth and/or development.
    
 
 0.645
CCSAP
Centriole, cilia and spindle associated protein.
      
 0.567
KAT14
N-acetyltransferase domain-containing protein.
      
 0.560
OMG
Oligodendrocyte myelin glycoprotein.
    
 
 0.552
NOL6
Nucleolar protein 6.
      
 0.510
DCAF12L2
DDB1- and CUL4-associated factor 12; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
      
 0.482
CEP76
Centrosomal protein 76.
      
 0.481
SNX25
Sorting nexin 25.
      
 0.458
SNRNP35
RRM domain-containing protein.
      
 0.437
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (18%) [HD]