STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNMB4Uncharacterized protein. (211 aa)    
Predicted Functional Partners:
KCNU1
Uncharacterized protein.
    
 0.959
KCNMB1
Putative calcium-activated potassium channel regulatory subunit.
     
0.939
KCNMA1
Calcium-activated potassium channel subunit alpha-1; Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in t [...]
    
 0.912
PRKACB
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
 0.911
KCNMB2
KcnmB2_inactiv domain-containing protein.
   
 
 
0.903
PRKG1
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
  0.900
KCNT1
Potassium channel subfamily T member 1; Generates outwardly rectifying currents that are suppressed by elevation of intracellular calcium; Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa4.1/KCNT1 sub-subfamily.
    
 
 0.845
CLC2DL4
C-type lectin domain-containing protein.
      
 0.842
ANKRD24
Ankyrin repeat domain 24.
      
 0.745
RDM1
RAD52 motif-containing protein 1; Confers resistance to the antitumor agent cisplatin. Binds preferentially to sites of DNA modified by cisplatin in vitro. Binds to double-stranded DNA in a cooperative manner resulting in the formation of filament-like structures. Binds to single-stranded DNA with no cooperativity. Binds to RNA.
      
 0.704
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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