STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKR1A1Aldo-keto reductase family 1 member A1; Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosaccharides and bile acids. Acts as an aldehyde-detoxification enzyme (By similarity). Displays no reductase activity towards retinoids (By similarity). (365 aa)    
Predicted Functional Partners:
ALDH3A2
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.958
ALDH7A1
Aldehyde dehydrogenase 7 family member A1; Belongs to the aldehyde dehydrogenase family.
   
 0.947
ALDH9A1
Aldehyde dehydrogenase 9 family member A1; Belongs to the aldehyde dehydrogenase family.
   
 0.944
ADH4
S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
   
 0.919
CRYL1
Uncharacterized protein.
   
 
 0.919
GUSB
Uncharacterized protein.
  
 
 0.915
ADH6
PKS_ER domain-containing protein.
   
 0.913
GK2
Uncharacterized protein; Belongs to the FGGY kinase family.
  
 
 0.913
ADH1C
Alcohol dehydrogenase 1.
   
 0.913
KL
Klotho.
     
 0.907
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.