EPS15 protein (Gallus gallus) - STRING interaction network

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

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Score

EPS15

Uncharacterized protein. (919 aa)

Predicted Functional Partners:

ITSN2

0.994

STON2

0.983

EPN2

0.980

FCHO1

0.959

EGFR

0.951

HGS

0.939

CLTCL1

0.935

CLTC

0.931

ITSN1

0.927

PDGFRA

0.914

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLTC	CLTCL1	ENSGALP00000008236	ENSGALP00000048174	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.904
CLTC	EGFR	ENSGALP00000008236	ENSGALP00000053328	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...]	0.531
CLTC	EPN2	ENSGALP00000008236	ENSGALP00000074208	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	ENTH domain-containing protein.	0.941
CLTC	EPS15	ENSGALP00000008236	ENSGALP00000017141	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.931
CLTC	FCHO1	ENSGALP00000008236	ENSGALP00000067704	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	FCH domain only 1.	0.633
CLTC	HGS	ENSGALP00000008236	ENSGALP00000011677	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.820
CLTC	ITSN1	ENSGALP00000008236	ENSGALP00000047474	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Intersectin 1.	0.843
CLTC	ITSN2	ENSGALP00000008236	ENSGALP00000074049	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Intersectin 2.	0.880
CLTC	STON2	ENSGALP00000008236	ENSGALP00000017195	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family.	0.666
CLTCL1	CLTC	ENSGALP00000048174	ENSGALP00000008236	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.904
CLTCL1	EPN2	ENSGALP00000048174	ENSGALP00000074208	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	ENTH domain-containing protein.	0.938
CLTCL1	EPS15	ENSGALP00000048174	ENSGALP00000017141	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.935
CLTCL1	FCHO1	ENSGALP00000048174	ENSGALP00000067704	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	FCH domain only 1.	0.643
CLTCL1	HGS	ENSGALP00000048174	ENSGALP00000011677	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Hepatocyte growth factor-regulated tyrosine kinase substrate.	0.714
CLTCL1	ITSN1	ENSGALP00000048174	ENSGALP00000047474	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Intersectin 1.	0.851
CLTCL1	ITSN2	ENSGALP00000048174	ENSGALP00000074049	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Intersectin 2.	0.888
CLTCL1	STON2	ENSGALP00000048174	ENSGALP00000017195	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family.	0.403
EGFR	CLTC	ENSGALP00000053328	ENSGALP00000008236	Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...]	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.531
EGFR	EPN2	ENSGALP00000053328	ENSGALP00000074208	Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...]	ENTH domain-containing protein.	0.915
EGFR	EPS15	ENSGALP00000053328	ENSGALP00000017141	Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...]	Uncharacterized protein.	0.951