STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP3K2Protein kinase domain-containing protein. (142 aa)    
Predicted Functional Partners:
MAP2K5
Uncharacterized protein.
  
0.992
PAK2
Non-specific serine/threonine protein kinase.
  
0.925
PAK1
Non-specific serine/threonine protein kinase.
  
 
0.924
LOC420419
Uncharacterized protein.
  
 
0.913
MAP3K3
Mitogen-activated protein kinase kinase kinase 3.
  
 
0.913
MAP2K3
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
  
0.912
MAP2K6
Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily.
  
0.912
SMYD3
SET and MYND domain containing 3.
   
 
 0.908
SRC
Proto-oncogene tyrosine-protein kinase Src; Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy bet [...]
    
 0.907
GNAO1
Uncharacterized protein.
    
 
 0.745
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.