STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC93Coiled-coil domain-containing protein 93; May be involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery. Belongs to the CCDC93 family. (617 aa)    
Predicted Functional Partners:
COMMD8
COMM domain-containing protein.
   
 
 0.882
FKBP15
Peptidylprolyl isomerase.
   
  
 0.869
COMMD10
COMM domain-containing protein.
    
 
 0.854
COMMD1
Copper metabolism domain containing 1.
   
 
 0.828
VPS26C
VPS26 endosomal protein sorting factor C.
    
 
 0.816
VPS35L
VPS35 endosomal protein sorting factor like.
    
 
 0.814
VPS29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity). Acts also as component of the retriever complex. The retriever complex is an heterotrimeric complex related to retromer cargo-selective com [...]
    
 
 0.788
COMMD5
COMM domain-containing protein.
    
 
 0.770
COMMD2
COMM domain containing 2.
    
 
 0.766
COMMD6
COMM domain containing 6.
   
 
 0.765
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.