Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARL14EPARF7EP_C domain-containing protein. (276 aa)    
Predicted Functional Partners:
ATF7IP
Activating transcription factor 7-interacting protein 1; Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing histone methyltransferase activity. May belong to a complex that represses transcription and couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) (By similarity); Belongs to the MCAF family.
  
 
 
 0.980
SETDB2
SET domain bifurcated histone lysine methyltransferase 2.
    
 
 0.963
SETDB1
SET domain bifurcated histone lysine methyltransferase 1.
    
 
 0.823
OSCP1
Organic solute carrier partner 1.
      
 0.675
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
   0.619
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
   0.619
KIF21A
Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.601
VHL
Uncharacterized protein.
    
   0.581
PDRG1
P53 and DNA damage regulated 1.
      
 0.572
SUOX
Sulfite oxidase.
      
 0.535
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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