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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FSHBFollicle stimulating hormone, beta polypeptide. (131 aa)    
Predicted Functional Partners:
CGA
Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.
   
 0.997
FSHR
Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
   
 0.992
NPVF
Gonadotropin-inhibitory hormone.
   
  
 0.953
GNRHR
Type 1/III gonadotropin-releasing hormone receptor hexahelical variant.
   
  
 0.927
PRL
Prolactin.
   
  
 0.885
CGNRH-R
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
   
  
 0.853
GNRH1
GnRH-associated peptide 1; Stimulates the secretion of gonadotropins; Belongs to the GnRH family.
   
  
 0.837
POMC
Uncharacterized protein.
   
  
 0.824
LHCGR
Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
   
 
 0.800
MRPS26
28S ribosomal protein S26, mitochondrial.
      
 0.781
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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