node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHUK | IRAK2 | ENSGALP00000051589 | ENSGALP00000072173 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | Protein kinase domain-containing protein. | 0.517 |
CHUK | IRAK4 | ENSGALP00000051589 | ENSGALP00000015599 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | Protein kinase domain-containing protein. | 0.949 |
CHUK | MAP3K7 | ENSGALP00000051589 | ENSGALP00000043939 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | Mitogen-activated protein kinase kinase kinase 7. | 0.972 |
CHUK | RIPK1 | ENSGALP00000051589 | ENSGALP00000036418 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | Uncharacterized protein. | 0.967 |
CHUK | TAB1 | ENSGALP00000051589 | ENSGALP00000019817 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | PPM-type phosphatase domain-containing protein. | 0.982 |
CHUK | TAB2 | ENSGALP00000051589 | ENSGALP00000020155 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. | 0.972 |
CHUK | TAB3 | ENSGALP00000051589 | ENSGALP00000026205 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. | 0.738 |
CHUK | TLR3 | ENSGALP00000051589 | ENSGALP00000021914 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | Toll-like receptor 3; Belongs to the Toll-like receptor family. | 0.713 |
CHUK | TRADD | ENSGALP00000051589 | ENSGALP00000005055 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | TNFRSF1A associated via death domain. | 0.904 |
CHUK | TRAF6 | ENSGALP00000051589 | ENSGALP00000068399 | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.996 |
IRAK2 | CHUK | ENSGALP00000072173 | ENSGALP00000051589 | Protein kinase domain-containing protein. | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | 0.517 |
IRAK2 | IRAK4 | ENSGALP00000072173 | ENSGALP00000015599 | Protein kinase domain-containing protein. | Protein kinase domain-containing protein. | 0.961 |
IRAK2 | MAP3K7 | ENSGALP00000072173 | ENSGALP00000043939 | Protein kinase domain-containing protein. | Mitogen-activated protein kinase kinase kinase 7. | 0.718 |
IRAK2 | TAB1 | ENSGALP00000072173 | ENSGALP00000019817 | Protein kinase domain-containing protein. | PPM-type phosphatase domain-containing protein. | 0.787 |
IRAK2 | TAB2 | ENSGALP00000072173 | ENSGALP00000020155 | Protein kinase domain-containing protein. | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. | 0.967 |
IRAK2 | TAB3 | ENSGALP00000072173 | ENSGALP00000026205 | Protein kinase domain-containing protein. | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. | 0.896 |
IRAK2 | TLR3 | ENSGALP00000072173 | ENSGALP00000021914 | Protein kinase domain-containing protein. | Toll-like receptor 3; Belongs to the Toll-like receptor family. | 0.678 |
IRAK2 | TRAF6 | ENSGALP00000072173 | ENSGALP00000068399 | Protein kinase domain-containing protein. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.999 |
IRAK4 | CHUK | ENSGALP00000015599 | ENSGALP00000051589 | Protein kinase domain-containing protein. | Inhibitor of nuclear factor kappa-B kinase subunit alpha; Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Phosphorylates 'Ser-10' of histone H3 at NF-kappa-B-regulated promoters during inflammatory responses triggered by cytokines; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. I-kappa-B kinase subfamily. | 0.949 |
IRAK4 | IRAK2 | ENSGALP00000015599 | ENSGALP00000072173 | Protein kinase domain-containing protein. | Protein kinase domain-containing protein. | 0.961 |