STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIMP3Metalloproteinase inhibitor 3; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli (212 aa)    
Predicted Functional Partners:
ADAM17
Tumor necrosis factor alpha converting enzyme; Disintegrin and metalloproteinase domain-containing protein 17 precursor
    
 
 0.927
SERPINA1
Uncharacterized protein; Gallus gallus serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1), mRNA; Belongs to the serpin family
   
 
 0.909
SEPP1
Gallus gallus selenoprotein P, plasma, 1 (SEPP1), mRNA
   
 
 0.903
ITIH3
Uncharacterized protein; Inter-alpha-trypsin inhibitor heavy chain 3
   
 
  0.901
RARRES2
Chemerin; Gallus gallus retinoic acid receptor responder (tazarotene induced) 2 (RARRES2), transcript variant 2, mRNA
   
 
  0.901
SERPINA5
Uncharacterized protein; Belongs to the serpin family
   
 
  0.901
SERPINA9
Uncharacterized protein; Belongs to the serpin family
   
 
  0.901
SERPINA4
Uncharacterized protein; Gallus gallus serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 (SERPINA4), mRNA; Belongs to the serpin family
   
 
  0.901
CLEC3B
Gallus gallus C-type lectin domain family 3, member B (CLEC3B), mRNA
   
 
  0.901
APOH
Gallus gallus apolipoprotein H (beta-2-glycoprotein I) (APOH), mRNA
     
  0.900
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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