STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIVEP1Human immunodeficiency virus type I enhancer binding protein 1. (2710 aa)    
Predicted Functional Partners:
SPEN
Spen family transcriptional repressor.
   
 
 0.678
TUBGCP6
Tubulin gamma complex associated protein 6.
   
 
 0.616
MED14
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
 
 0.559
KIDINS220
Kinase D interacting substrate 220.
   
 
 0.553
NCOA3
Nuclear receptor coactivator.
   
 
 0.546
TBC1D24
Uncharacterized protein.
      
 0.539
NCOA2
Nuclear receptor coactivator.
   
 
 0.536
GTF2B
General transcription factor IIB.
    
 
 0.531
PTCHD4
SSD domain-containing protein.
      
 0.522
UBE2A
Ubiquitin-conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.514
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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