STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SGCZSarcoglycan zeta. (401 aa)    
Predicted Functional Partners:
SGCA
CADG domain-containing protein.
   
 0.800
SSPN
Sarcospan.
   
 0.773
GALNT9
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.762
LEPROTL1
Leptin receptor overlapping transcript like 1.
      
 0.742
SGCE
Sarcoglycan epsilon.
   
 0.708
SGCG
Sarcoglycan gamma.
  
 
0.707
SRD5A3
Steroid 5 alpha-reductase 3.
      
 0.703
DAG1
Peptidase S72 domain-containing protein.
    
 0.686
LOC101750972
Peptidase S72 domain-containing protein.
    
 0.686
DNAJB6
DnaJ homolog subfamily B member 6; Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (By similarity). Has a stimulatory effect on the ATPase activity of HSP70 in a dose- dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity (By similarity).
    
 
 0.656
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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