node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CDHR3 | PIFO | ENSGALP00000067446 | ENSGALP00000038994 | Uncharacterized protein. | Primary cilia formation. | 0.525 |
CDHR3 | TXLNB | ENSGALP00000067446 | ENSGALP00000070442 | Uncharacterized protein. | Beta-taxilin; Promotes neurite-outgrowth. May be involved in intracellular vesicle traffic. | 0.623 |
CPLX3 | TXLNB | ENSGALP00000041734 | ENSGALP00000070442 | Uncharacterized protein. | Beta-taxilin; Promotes neurite-outgrowth. May be involved in intracellular vesicle traffic. | 0.607 |
LRRC17 | TXLNB | ENSGALP00000068341 | ENSGALP00000070442 | p37NB protein. | Beta-taxilin; Promotes neurite-outgrowth. May be involved in intracellular vesicle traffic. | 0.686 |
MASTL | NCLN | ENSGALP00000012119 | ENSGALP00000046135 | Serine/threonine-protein kinase greatwall; Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser- 62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity hi [...] | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family. | 0.596 |
MASTL | PAFAH2 | ENSGALP00000012119 | ENSGALP00000069345 | Serine/threonine-protein kinase greatwall; Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser- 62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity hi [...] | Platelet-activating factor acetylhydrolase. | 0.678 |
MASTL | PPP6R3 | ENSGALP00000012119 | ENSGALP00000067566 | Serine/threonine-protein kinase greatwall; Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser- 62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity hi [...] | Serine/threonine-protein phosphatase 6 regulatory subunit 3; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit (By similarity); Belongs to the SAPS family. | 0.673 |
MASTL | TBC1D12 | ENSGALP00000012119 | ENSGALP00000048430 | Serine/threonine-protein kinase greatwall; Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser- 62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity hi [...] | TBC1 domain family member 12. | 0.583 |
MASTL | TXLNB | ENSGALP00000012119 | ENSGALP00000070442 | Serine/threonine-protein kinase greatwall; Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser- 62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity hi [...] | Beta-taxilin; Promotes neurite-outgrowth. May be involved in intracellular vesicle traffic. | 0.588 |
NCLN | MASTL | ENSGALP00000046135 | ENSGALP00000012119 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family. | Serine/threonine-protein kinase greatwall; Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser- 62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity hi [...] | 0.596 |
NCLN | PAFAH2 | ENSGALP00000046135 | ENSGALP00000069345 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family. | Platelet-activating factor acetylhydrolase. | 0.711 |
NCLN | PPP6R3 | ENSGALP00000046135 | ENSGALP00000067566 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family. | Serine/threonine-protein phosphatase 6 regulatory subunit 3; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit (By similarity); Belongs to the SAPS family. | 0.723 |
NCLN | TBC1D12 | ENSGALP00000046135 | ENSGALP00000048430 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family. | TBC1 domain family member 12. | 0.672 |
NCLN | TXLNB | ENSGALP00000046135 | ENSGALP00000070442 | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family. | Beta-taxilin; Promotes neurite-outgrowth. May be involved in intracellular vesicle traffic. | 0.629 |
PAFAH2 | MASTL | ENSGALP00000069345 | ENSGALP00000012119 | Platelet-activating factor acetylhydrolase. | Serine/threonine-protein kinase greatwall; Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser- 62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity hi [...] | 0.678 |
PAFAH2 | NCLN | ENSGALP00000069345 | ENSGALP00000046135 | Platelet-activating factor acetylhydrolase. | Nicalin; May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning; Belongs to the nicastrin family. | 0.711 |
PAFAH2 | PPP6R3 | ENSGALP00000069345 | ENSGALP00000067566 | Platelet-activating factor acetylhydrolase. | Serine/threonine-protein phosphatase 6 regulatory subunit 3; Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit (By similarity); Belongs to the SAPS family. | 0.765 |
PAFAH2 | TBC1D12 | ENSGALP00000069345 | ENSGALP00000048430 | Platelet-activating factor acetylhydrolase. | TBC1 domain family member 12. | 0.740 |
PAFAH2 | TXLNB | ENSGALP00000069345 | ENSGALP00000070442 | Platelet-activating factor acetylhydrolase. | Beta-taxilin; Promotes neurite-outgrowth. May be involved in intracellular vesicle traffic. | 0.706 |
PIFO | CDHR3 | ENSGALP00000038994 | ENSGALP00000067446 | Primary cilia formation. | Uncharacterized protein. | 0.525 |