STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHC1Uncharacterized protein. (990 aa)    
Predicted Functional Partners:
CBX7
Chromobox 7.
    
 0.929
CBX8
Chromobox 8.
    
 0.924
CBX2
Chromobox 2.
    
 0.901
RNF2
Ring finger protein 2.
    
 0.888
CBX4
Chromo domain-containing protein.
    
 0.885
BMI1
Polycomb complex protein BMI-1; Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2/RING2.
    
 0.872
PCGF2
RING-type domain-containing protein.
    
 0.872
SCMH1
Scm polycomb group protein homolog 1.
    
 0.842
PHC3
Polyhomeotic homolog 3.
     
 
0.800
CBX6
Chromobox 6.
    
 0.695
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.