node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTBP1 | CTBP2-2 | ENSGALP00000065527 | ENSGALP00000070771 | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Uncharacterized protein. | 0.996 |
CTBP1 | HDAC1 | ENSGALP00000065527 | ENSGALP00000059784 | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | 0.958 |
CTBP1 | HDAC2 | ENSGALP00000065527 | ENSGALP00000057637 | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). | 0.969 |
CTBP1 | RBPJ | ENSGALP00000065527 | ENSGALP00000069295 | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Recombination signal binding protein for immunoglobulin kappa J region. | 0.929 |
CTBP1 | SIN3A | ENSGALP00000065527 | ENSGALP00000002508 | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | HDAC_interact domain-containing protein. | 0.422 |
CTBP2-2 | CTBP1 | ENSGALP00000070771 | ENSGALP00000065527 | Uncharacterized protein. | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.996 |
CTBP2-2 | HDAC1 | ENSGALP00000070771 | ENSGALP00000059784 | Uncharacterized protein. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | 0.931 |
CTBP2-2 | HDAC2 | ENSGALP00000070771 | ENSGALP00000057637 | Uncharacterized protein. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). | 0.944 |
CTBP2-2 | RBPJ | ENSGALP00000070771 | ENSGALP00000069295 | Uncharacterized protein. | Recombination signal binding protein for immunoglobulin kappa J region. | 0.913 |
HDAC1 | CTBP1 | ENSGALP00000059784 | ENSGALP00000065527 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.958 |
HDAC1 | CTBP2-2 | ENSGALP00000059784 | ENSGALP00000070771 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | Uncharacterized protein. | 0.931 |
HDAC1 | HDAC2 | ENSGALP00000059784 | ENSGALP00000057637 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). | 0.994 |
HDAC1 | NCOR2 | ENSGALP00000059784 | ENSGALP00000073350 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | Nuclear receptor corepressor 2. | 0.949 |
HDAC1 | RB1 | ENSGALP00000059784 | ENSGALP00000071459 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Also acts as a transcription repressor of E2F target genes by recruiting c [...] | 0.966 |
HDAC1 | RBBP4 | ENSGALP00000059784 | ENSGALP00000005565 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. | 0.996 |
HDAC1 | RBBP7 | ENSGALP00000059784 | ENSGALP00000026647 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. | 0.996 |
HDAC1 | RBPJ | ENSGALP00000059784 | ENSGALP00000069295 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | Recombination signal binding protein for immunoglobulin kappa J region. | 0.945 |
HDAC1 | SIN3A | ENSGALP00000059784 | ENSGALP00000002508 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | HDAC_interact domain-containing protein. | 0.997 |
HDAC1 | SIN3B | ENSGALP00000059784 | ENSGALP00000005972 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity); Belongs to the histone deacetylase family. HD type 1 subfamily. | SIN3 transcription regulator family member B. | 0.974 |
HDAC2 | CTBP1 | ENSGALP00000057637 | ENSGALP00000065527 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). | Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.969 |