Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC80Coiled-coil domain-containing protein 80; Promotes cell adhesion and matrix assembly (By similarity). May play a role in eye formation. (958 aa)    
Predicted Functional Partners:
DCN
Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
   
 
 0.986
BRS3
Bombesin-like peptide receptor subtype 3.5; Belongs to the G-protein coupled receptor 1 family.
      
 0.810
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
   0.539
POSTN
Uncharacterized protein.
   
  
 0.484
COL6A1
Collagen alpha-1(VI) chain; Collagen VI acts as a cell-binding protein; Belongs to the type VI collagen family.
   
  
 0.475
ECM2
Extracellular matrix protein 2.
   
 
 0.463
FBLN2
Fibulin 2.
   
 
 0.457
CKAP2
Uncharacterized protein.
  
    0.426
SPERT
Protein chibby homolog 2; Belongs to the chibby family. SPERT subfamily.
  
 
   0.420
TM4SF19
Uncharacterized protein.
  
     0.412
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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