Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CBLB | EGFR | ENSGALP00000024726 | ENSGALP00000053328 | Cbl proto-oncogene B. | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...] | 0.961 |
| CBLB | INSR | ENSGALP00000024726 | ENSGALP00000048413 | Cbl proto-oncogene B. | Tyrosine-protein kinase receptor. | 0.921 |
| CBLB | ITCH | ENSGALP00000024726 | ENSGALP00000055208 | Cbl proto-oncogene B. | E3 ubiquitin-protein ligase. | 0.917 |
| CBLB | LOC107055431 | ENSGALP00000024726 | ENSGALP00000054960 | Cbl proto-oncogene B. | Uncharacterized protein. | 0.917 |
| CBLB | MET | ENSGALP00000024726 | ENSGALP00000054618 | Cbl proto-oncogene B. | Uncharacterized protein. | 0.922 |
| CBLB | NEDD4 | ENSGALP00000024726 | ENSGALP00000006925 | Cbl proto-oncogene B. | E3 ubiquitin-protein ligase. | 0.917 |
| CBLB | SH3KBP1 | ENSGALP00000024726 | ENSGALP00000026438 | Cbl proto-oncogene B. | Uncharacterized protein. | 0.920 |
| CBLB | SYK | ENSGALP00000024726 | ENSGALP00000024509 | Cbl proto-oncogene B. | Tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can a [...] | 0.959 |
| CBLB | TRAF6 | ENSGALP00000024726 | ENSGALP00000068399 | Cbl proto-oncogene B. | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.931 |
| CBLB | WWP1 | ENSGALP00000024726 | ENSGALP00000050028 | Cbl proto-oncogene B. | E3 ubiquitin-protein ligase. | 0.917 |
| EGFR | CBLB | ENSGALP00000053328 | ENSGALP00000024726 | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...] | Cbl proto-oncogene B. | 0.961 |
| EGFR | ITCH | ENSGALP00000053328 | ENSGALP00000055208 | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...] | E3 ubiquitin-protein ligase. | 0.683 |
| EGFR | LOC107055431 | ENSGALP00000053328 | ENSGALP00000054960 | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...] | Uncharacterized protein. | 0.691 |
| EGFR | MET | ENSGALP00000053328 | ENSGALP00000054618 | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...] | Uncharacterized protein. | 0.715 |
| EGFR | NEDD4 | ENSGALP00000053328 | ENSGALP00000006925 | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...] | E3 ubiquitin-protein ligase. | 0.743 |
| EGFR | SH3KBP1 | ENSGALP00000053328 | ENSGALP00000026438 | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...] | Uncharacterized protein. | 0.723 |
| EGFR | TRAF6 | ENSGALP00000053328 | ENSGALP00000068399 | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...] | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. | 0.754 |
| EGFR | WWP1 | ENSGALP00000053328 | ENSGALP00000050028 | Epidermal growth factor receptor; Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF and TGFA/TGF-alpha. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues (By similarity). The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades (By similarity). Activates at least 4 major downstream signaling cascades including [...] | E3 ubiquitin-protein ligase. | 0.684 |
| INSR | CBLB | ENSGALP00000048413 | ENSGALP00000024726 | Tyrosine-protein kinase receptor. | Cbl proto-oncogene B. | 0.921 |
| ITCH | CBLB | ENSGALP00000055208 | ENSGALP00000024726 | E3 ubiquitin-protein ligase. | Cbl proto-oncogene B. | 0.917 |
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