GAK protein (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

GAK

J domain-containing protein. (287 aa)

Predicted Functional Partners:

ENSGALP00000073953

0.995

CLTC

0.965

CLTCL1

0.965

AAK1

0.953

EPN2

0.945

HIP1R

0.936

HIP1

0.936

CLTB

0.936

CLTA

0.936

EPN3

0.925

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAK1	CLTC	ENSGALP00000044757	ENSGALP00000008236	AP2 associated kinase 1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.545
AAK1	CLTCL1	ENSGALP00000044757	ENSGALP00000048174	AP2 associated kinase 1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.474
AAK1	ENSGALP00000073953	ENSGALP00000044757	ENSGALP00000073953	AP2 associated kinase 1.	Uncharacterized protein.	0.538
AAK1	EPN2	ENSGALP00000044757	ENSGALP00000074208	AP2 associated kinase 1.	ENTH domain-containing protein.	0.575
AAK1	GAK	ENSGALP00000044757	ENSGALP00000024729	AP2 associated kinase 1.	J domain-containing protein.	0.953
AAK1	HIP1	ENSGALP00000044757	ENSGALP00000052993	AP2 associated kinase 1.	Huntingtin interacting protein 1.	0.493
AAK1	HIP1R	ENSGALP00000044757	ENSGALP00000050552	AP2 associated kinase 1.	Uncharacterized protein.	0.739
CLTA	CLTB	ENSGALP00000069813	ENSGALP00000053603	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.903
CLTA	CLTC	ENSGALP00000069813	ENSGALP00000008236	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.994
CLTA	CLTCL1	ENSGALP00000069813	ENSGALP00000048174	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.994
CLTA	ENSGALP00000073953	ENSGALP00000069813	ENSGALP00000073953	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Uncharacterized protein.	0.936
CLTA	EPN2	ENSGALP00000069813	ENSGALP00000074208	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	ENTH domain-containing protein.	0.980
CLTA	EPN3	ENSGALP00000069813	ENSGALP00000072870	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Epsin 3.	0.962
CLTA	GAK	ENSGALP00000069813	ENSGALP00000024729	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	J domain-containing protein.	0.936
CLTA	HIP1	ENSGALP00000069813	ENSGALP00000052993	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Huntingtin interacting protein 1.	0.720
CLTA	HIP1R	ENSGALP00000069813	ENSGALP00000050552	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Uncharacterized protein.	0.913
CLTB	CLTA	ENSGALP00000053603	ENSGALP00000069813	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.903
CLTB	CLTC	ENSGALP00000053603	ENSGALP00000008236	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.994
CLTB	CLTCL1	ENSGALP00000053603	ENSGALP00000048174	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.994
CLTB	ENSGALP00000073953	ENSGALP00000053603	ENSGALP00000073953	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	Uncharacterized protein.	0.936