STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CASP8AP2Caspase 8 associated protein 2. (2028 aa)    
Predicted Functional Partners:
PAFAH2
Platelet-activating factor acetylhydrolase.
      
 0.700
WDR76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
      
 0.638
GINS2
DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family.
      
 0.622
DSCC1
DNA replication and sister chromatid cohesion 1.
      
 0.605
CLK3
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
  
 0.603
UCKL1
Uridine-cytidine kinase; Belongs to the uridine kinase family.
      
 0.600
UBR7
UBR-type domain-containing protein.
      
 0.589
PIK3R6
Phosphoinositide-3-kinase regulatory subunit 6.
      
 0.583
ATAD2
ATPase family AAA domain containing 2.
   
  
 0.560
PRIM1
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
   
  
 0.547
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.