STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VCANVersican core protein; May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid (2649 aa)    
Predicted Functional Partners:
DCN
Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily
   
 0.983
FN1
Fibronectin; Gallus gallus fibronectin 1 (FN1), mRNA
   
 
 0.969
FBN1
Fibrillin 1
   
 0.969
CHST11
Carbohydrate (chondroitin 4) sulfotransferase 11
   
 
 0.962
BCAN
Brevican
    
0.958
BMP4
Bone morphogenetic protein 4; Negatively regulates the structure and function of the limb apical ectodermal ridge
     
 0.946
SDC1
Syndecan; Cell surface proteoglycan
     
 0.938
SDC4
Syndecan-4; Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP
     
 0.935
GPC1
Glypican-1; Cell surface proteoglycan that bears heparan sulfate. Modulates Wnt-signaling pathway
   
 
 0.933
IGFBP4
Uncharacterized protein; Gallus gallus insulin-like growth factor binding protein 4 (IGFBP4), mRNA
     
 0.933
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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