STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM53AProtein FAM53A; May play an important role in neural development; the dorsomedial roof of the third ventricle. (418 aa)    
Predicted Functional Partners:
GTF3C3
Uncharacterized protein.
      
 0.742
GTF2E1
General transcription factor IIE subunit 1.
      
 0.742
SMG7
SMG7 nonsense mediated mRNA decay factor.
   
  
 0.704
PKP4
Uncharacterized protein.
   
  
 0.679
MBTPS1
Membrane bound transcription factor peptidase, site 1.
      
 0.675
SLBP
Histone stem-loop binding protein.
   
  
 0.643
TMEM129
Transmembrane protein 129.
   
  
 0.633
TACC3
TACC_C domain-containing protein.
   
  
 0.631
KPNA3
Importin subunit alpha; Belongs to the importin alpha family.
   
  
 0.624
NFYC
Nuclear transcription factor Y subunit gamma.
   
  
 0.600
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.