STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3687 aa)    
Predicted Functional Partners:
MPHOSPH6
Uncharacterized protein.
      
 0.745
RAMP2
Receptor activity modifying protein 2.
   
  
 0.721
ADAMTS14
ADAM metallopeptidase with thrombospondin type 1 motif 14.
   
 
 0.559
RAG1
V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break b [...]
    
 
 0.553
ADM
Uncharacterized protein.
      
 0.533
TEX2
Testis expressed 2.
    
 
 0.527
TDRD6
Tudor domain containing 6.
      
 0.525
SPATA6
Spermatogenesis associated 6.
      
 0.522
RIPK4
Receptor interacting serine/threonine kinase 4.
   
 
 0.518
GCC2
GRIP and coiled-coil domain containing 2.
    
 
 0.516
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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