ASXL2 protein (Gallus gallus) - STRING interaction network

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ASXL2

Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...] (1550 aa)

Predicted Functional Partners:

BAP1

0.997

KDM1B

0.963

ASXL3

0.930

ASXL1

0.928

MBD5

0.922

FOXK2

0.853

FOXK1

0.829

EZH1

0.823

OGT

0.817

EED

0.755

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASXL1	ASXL2	ENSGALP00000010661	ENSGALP00000026627	ASXL transcriptional regulator 1.	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	0.928
ASXL1	ASXL3	ENSGALP00000010661	ENSGALP00000024470	ASXL transcriptional regulator 1.	ASXL transcriptional regulator 3.	0.914
ASXL1	BAP1	ENSGALP00000010661	ENSGALP00000006954	ASXL transcriptional regulator 1.	Ubiquitin carboxyl-terminal hydrolase BAP1; Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1) (By similarity); Belongs to the peptidase C12 family. BAP1 subfamily.	0.845
ASXL1	FOXK1	ENSGALP00000010661	ENSGALP00000007086	ASXL transcriptional regulator 1.	Forkhead box K1.	0.613
ASXL1	FOXK2	ENSGALP00000010661	ENSGALP00000002394	ASXL transcriptional regulator 1.	Forkhead box K2.	0.647
ASXL1	OGT	ENSGALP00000010661	ENSGALP00000046311	ASXL transcriptional regulator 1.	O-linked N-acetylglucosamine (GlcNAc) transferase.	0.426
ASXL2	ASXL1	ENSGALP00000026627	ENSGALP00000010661	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	ASXL transcriptional regulator 1.	0.928
ASXL2	ASXL3	ENSGALP00000026627	ENSGALP00000024470	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	ASXL transcriptional regulator 3.	0.930
ASXL2	BAP1	ENSGALP00000026627	ENSGALP00000006954	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	Ubiquitin carboxyl-terminal hydrolase BAP1; Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1) (By similarity); Belongs to the peptidase C12 family. BAP1 subfamily.	0.997
ASXL2	EED	ENSGALP00000026627	ENSGALP00000057840	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity).	0.755
ASXL2	EZH1	ENSGALP00000026627	ENSGALP00000056397	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	Enhancer of zeste 1 polycomb repressive complex 2 subunit.	0.823
ASXL2	FOXK1	ENSGALP00000026627	ENSGALP00000007086	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	Forkhead box K1.	0.829
ASXL2	FOXK2	ENSGALP00000026627	ENSGALP00000002394	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	Forkhead box K2.	0.853
ASXL2	KDM1B	ENSGALP00000026627	ENSGALP00000020669	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	Lysine demethylase 1B.	0.963
ASXL2	MBD5	ENSGALP00000026627	ENSGALP00000020324	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	Methyl-CpG binding domain protein 5.	0.922
ASXL2	OGT	ENSGALP00000026627	ENSGALP00000046311	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	O-linked N-acetylglucosamine (GlcNAc) transferase.	0.817
ASXL3	ASXL1	ENSGALP00000024470	ENSGALP00000010661	ASXL transcriptional regulator 3.	ASXL transcriptional regulator 1.	0.914
ASXL3	ASXL2	ENSGALP00000024470	ENSGALP00000026627	ASXL transcriptional regulator 3.	Putative Polycomb group protein ASXL2; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors (B [...]	0.930
ASXL3	BAP1	ENSGALP00000024470	ENSGALP00000006954	ASXL transcriptional regulator 3.	Ubiquitin carboxyl-terminal hydrolase BAP1; Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1) (By similarity); Belongs to the peptidase C12 family. BAP1 subfamily.	0.981
ASXL3	EED	ENSGALP00000024470	ENSGALP00000057840	ASXL transcriptional regulator 3.	Polycomb protein EED; Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene (By similarity).	0.599

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