PGR protein (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PGR

Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (787 aa)

Predicted Functional Partners:

ESR1

0.974

PIK3CA

0.936

PRKACB

0.935

PIK3R2

0.923

FKBP4

0.917

PIK3R3

0.909

PIK3R1

0.909

MAPK14

0.908

MAPK12

0.907

MAPK11

0.907

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ESR1	FKBP4	ENSGALP00000073938	ENSGALP00000070868	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Peptidylprolyl isomerase.	0.648
ESR1	PGR	ENSGALP00000073938	ENSGALP00000027736	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.974
ESR1	PIK3CA	ENSGALP00000073938	ENSGALP00000014504	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.799
ESR1	PIK3R1	ENSGALP00000073938	ENSGALP00000067669	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Phosphoinositide-3-kinase regulatory subunit 1.	0.703
ESR1	PIK3R2	ENSGALP00000073938	ENSGALP00000005414	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Uncharacterized protein.	0.673
ESR1	PIK3R3	ENSGALP00000073938	ENSGALP00000023820	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Uncharacterized protein.	0.673
ESR1	PRKACB	ENSGALP00000073938	ENSGALP00000041979	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.504
FKBP4	ESR1	ENSGALP00000070868	ENSGALP00000073938	Peptidylprolyl isomerase.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.648
FKBP4	PGR	ENSGALP00000070868	ENSGALP00000027736	Peptidylprolyl isomerase.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.917
MAPK11	MAPK12	ENSGALP00000055637	ENSGALP00000014011	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.914
MAPK11	MAPK14	ENSGALP00000055637	ENSGALP00000052690	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.901
MAPK11	PGR	ENSGALP00000055637	ENSGALP00000027736	Mitogen-activated protein kinase.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.907
MAPK12	MAPK11	ENSGALP00000014011	ENSGALP00000055637	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.914
MAPK12	MAPK14	ENSGALP00000014011	ENSGALP00000052690	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.913
MAPK12	PGR	ENSGALP00000014011	ENSGALP00000027736	Mitogen-activated protein kinase.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.907
MAPK14	MAPK11	ENSGALP00000052690	ENSGALP00000055637	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.901
MAPK14	MAPK12	ENSGALP00000052690	ENSGALP00000014011	Mitogen-activated protein kinase.	Mitogen-activated protein kinase.	0.913
MAPK14	PGR	ENSGALP00000052690	ENSGALP00000027736	Mitogen-activated protein kinase.	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.908
PGR	ESR1	ENSGALP00000027736	ENSGALP00000073938	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.974
PGR	FKBP4	ENSGALP00000027736	ENSGALP00000070868	Progesterone receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Peptidylprolyl isomerase.	0.917

page 1 of 3

Server load: low (36%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About