STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGIF2TGFB induced factor homeobox 2. (545 aa)    
Predicted Functional Partners:
SMAD3
Mothers against decapentaplegic homolog 3; Transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinase. SMAD3 is a receptor- regulated SMAD (R-SMAD) (By similarity).
    
 0.925
SMAD2Z
Mothers against decapentaplegic homolog.
    
 0.921
TGIF1
Homeobox protein AKR; Binds to the F' element of the APOVLDLII gene and represses its transcription; Belongs to the TALE/TGIF homeobox family.
  
  
0.911
LOC769000
Mothers against decapentaplegic homolog.
    
 0.908
GMEB1
Glucocorticoid modulatory element binding protein 1.
   
  
 0.542
ZHX3
Zinc fingers and homeoboxes 3.
   
 
 0.522
SKIL
c-SKI_SMAD_bind domain-containing protein.
      
 0.516
HHEX
Hematopoietically-expressed homeobox protein HHEX; Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation.
   
 
 0.473
PPIG
Peptidylprolyl isomerase G.
   
  
 0.469
CDYL2
Chromodomain Y like 2.
      
 0.441
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.