STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB6ARas-related protein Rab-6A; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Involved in COPI-independent retrograde transport from the Golgi to the ER. Belongs to the small GTPase superfamily. Rab family. (208 aa)    
Predicted Functional Partners:
GDI1
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.953
GCC2
GRIP and coiled-coil domain containing 2.
    
 0.847
ARL1
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
   
 0.847
VPS39
CNH domain-containing protein.
    
 
 0.844
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
    
 0.836
BICD2
BICD cargo adaptor 2.
    
 0.802
BICD1
BICD cargo adaptor 1.
    
 0.802
VPS53
Vacuolar protein sorting-associated protein 53 homolog; Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). Acts as component of the EARP complex that is involved in endocytic recycling.
   
 0.786
CRACR2B
Calcium release activated channel regulator 2B.
 
      0.782
RAB3GAP2
Uncharacterized protein.
   
 
 0.749
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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