STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKP1Plakophilin 1. (683 aa)    
Predicted Functional Partners:
JUP
Plakoglobin.
   
 0.938
DSG2
Desmoglein 2.
   
 0.903
DSP
Desmoplakin.
   
 0.849
DSC1
Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
   
 0.826
PERP2
Uncharacterized protein.
   
 
 0.816
CASP3
Caspase-3; Belongs to the peptidase C14A family.
    
  0.754
EVPL
SH3 domain-containing protein.
   
 
 0.721
PPL
Periplakin.
   
 
 0.678
PERP1
Uncharacterized protein.
   
  
 0.665
DSG4
Uncharacterized protein.
   
 0.660
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.